Probes containing gamma radiation detectors for in vivo tumor detection and imaging

N. E. Hartsough; H. B. Barber; J. M. Woolfenden; H. H. Barrett; T. S. Hickernell; D. P. Kwo

doi:10.1117/12.952174

Probes containing gamma radiation detectors for in vivo tumor detection and imaging

N. E. Hartsough, H. B. Barber, J. M. Woolfenden, H. H. Barrett, T. S. Hickernell, D. P. Kwo

Medical Imaging

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem; geometric background subtraction and imaging.

Original language	English (US)
Pages (from-to)	92-99
Number of pages	8
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	1068
DOIs	https://doi.org/10.1117/12.952174
State	Published - Aug 8 1989

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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abstract = "External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem; geometric background subtraction and imaging.",

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AU - Hartsough, N. E.

AU - Barber, H. B.

AU - Woolfenden, J. M.

AU - Barrett, H. H.

AU - Hickernell, T. S.

AU - Kwo, D. P.

PY - 1989/8/8

Y1 - 1989/8/8

N2 - External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem; geometric background subtraction and imaging.

AB - External gamma-camera imaging using tumor-seeking radiotracers has been shown to be insensitive in the task of identifying small tumors situated deep inside the body. Our approach is to use probes containing miniature radiation detectors which, when maneuvered close to a tumor, overcome the limitations of external imaging. We discuss our results from using such probes for bronchoscopic and surgical tumor detection. A limitation that prevents the detection of small tumors with these probes is the spatial variation of the background count rate due to distant background sources of high radiotracer uptake. We present two techniques for solving this problem; geometric background subtraction and imaging.

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Probes containing gamma radiation detectors for in vivo tumor detection and imaging

Abstract

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