Abstract
Prosthetic vascular graft infection remains one of the most challenging surgical problems for vascular surgeons. This condition is classically associated with high morbidity and mortality rates. Accurate diagnosis of a vascular graft infection can typically be made based on a thorough history and physical examination; although, infrequently, an extensive radiological evaluation is necessary to establish the clinical finding. Complete graft excision and extra-anatomic bypass grafting remains a commonly accepted surgical treatment strategy. Recent clinical data have supported other treatment modalities, including the use of in situ antibiotic-impregnated graft replacement, in situ allograft replacement and in situ autologous graft replacement. This article will review the pathobiology of aortic graft infection, as well as methods to prevent a prosthetic graft infection. Furthermore, various surgical treatment modalities of aortic graft infection will be discussed.
Original language | English (US) |
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Pages (from-to) | 305-315 |
Number of pages | 11 |
Journal | Expert Review of Anti-Infective Therapy |
Volume | 5 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2007 |
Externally published | Yes |
Keywords
- Allograft
- Aortoenteric fistula
- Cryopreserved vascular graft
- Extra-anatomic bypass
- Vascular graft excision
- Vascular graft infection
ASJC Scopus subject areas
- Microbiology
- Microbiology (medical)
- Virology
- Infectious Diseases