Abstract
We report a new sample preparation method that allows the direct transmission electron microscopy evaluation of the architectural characteristics of biomolecules entrapped in gel matrices. We demonstrate that this sample preparation technique can be used for the identification and ultrastructural characterization of liposomes, collagen I and collagen III embedded in gel matrices, and has the potential to be useful for transmission electron microscopy (TEM) characterization of other biomolecule-gel matrix systems.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 309-313 |
| Number of pages | 5 |
| Journal | Ultramicroscopy |
| Volume | 108 |
| Issue number | 4 |
| DOIs | |
| State | Published - Mar 2008 |
| Externally published | Yes |
Keywords
- Biomolecules
- Electron microscopy
- Gels
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Instrumentation
Fingerprint
Dive into the research topics of 'Preparation of biomolecule gel matrices for electron microscopy'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS