Preparation of an electrophilic glycine cation equivalent and its reaction with heteroatom nucleophiles

Martin J. O'Donnell, William D. Bennett, Robin L. Polt

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

A variety of heteroatom substituted Schiff base amino esters 4 - 7 are prepared either from the benzophenone imine of glycine ethyl ester (3) or by reaction of acetate 4 with heteroatom nucleophiles.

Original languageEnglish (US)
Pages (from-to)695-698
Number of pages4
JournalTetrahedron Letters
Volume26
Issue number6
DOIs
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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