Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose

Robert B. Hawkins; Helena L. Frischtak; Irving L. Kron; Ravi K. Ghanta

doi:10.1111/jocs.12764

Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose

Robert B. Hawkins, Helena L. Frischtak, Irving L. Kron, Ravi K. Ghanta

Medicine Administration

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60 Scopus citations

Abstract

We present the cases of two patients with bioprosthetic aortic valves who developed an allergy to alpha-gal. Each had premature degeneration of their bioprosthesis and demonstrated rapidly increasing transvalvular gradients after development of their allergy. Each underwent successful replacement with a mechanical aortic valve within 1–2 years of symptom onset. doi: 10.1111/jocs.12764 (J Card Surg 2016;31:446–448).

Original language	English (US)
Pages (from-to)	446-448
Number of pages	3
Journal	Journal of Cardiac Surgery
Volume	31
Issue number	7
DOIs	https://doi.org/10.1111/jocs.12764
State	Published - Jul 1 2016

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1111/jocs.12764

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abstract = "We present the cases of two patients with bioprosthetic aortic valves who developed an allergy to alpha-gal. Each had premature degeneration of their bioprosthesis and demonstrated rapidly increasing transvalvular gradients after development of their allergy. Each underwent successful replacement with a mechanical aortic valve within 1–2 years of symptom onset. doi: 10.1111/jocs.12764 (J Card Surg 2016;31:446–448).",

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Premature Bioprosthetic Aortic Valve Degeneration Associated with Allergy to Galactose-Alpha-1,3-Galactose

Abstract

ASJC Scopus subject areas

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