@inproceedings{cc78bf6c37f7405c910e058ca47011c6,
title = "Preliminary investigation of AdaptiSPECT-C designs with square or square and hexagonal detectors employing direct and oblique apertures",
abstract = "We report our investigation of system designs and 3D reconstruction for a dedicated brain-imaging SPECT system using multiple square or square and hexagonal detector modules. The system employs shuttering to vary which of multiple pinhole apertures are enabled to pass photons through to irradiate the detectors. Both multiplexed and nonmultiplexed irradiation by the pinholes are investigated. Sampling is assessed by simulated imaging of a uniform activity concentration in a spherical tub filling the VOI and a tailored Defrise phantom consisting of a series of activity containing slabs aligned axially. Potential image quality for clinical imaging is assessed through simulated imaging of an XCAT brain phantom with an activity distribution simulating perfusion imaging.",
keywords = "Brain Imaging, GPU, Image Reconstruction, Multi Pinhole, SPECT",
author = "Kalluri, {Kesava S.} and Navid Zeraatkar and Benjamin Auer and Kuo, {Philip H.} and Furenlid, {Lars R.} and King, {Michael A.}",
note = "Funding Information: Research reported in this publication was supported by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health under Award Number R01 EB022521. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; 15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine, Fully3D 2019 ; Conference date: 02-06-2019 Through 06-06-2019",
year = "2019",
doi = "10.1117/12.2534885",
language = "English (US)",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Samuel Matej and Metzler, {Scott D.}",
booktitle = "15th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine",
}