Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging

Yulun He; Arda Konik; Jan De Beenhouwer; Timothy J. Fromme; Clifford Lindsay; Kesava Kalluri; Xin Li; Neil C. Momsen; Lars R. Furenlid; Michael A. King

doi:10.1109/NSSMIC.2017.8533023

Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging

Yulun He, Arda Konik, Jan De Beenhouwer, Timothy J. Fromme, Clifford Lindsay, Kesava Kalluri, Xin Li, Neil C. Momsen, Lars R. Furenlid, Michael A. King

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

A mechanical design is reported for constructing a multi-pinhole (MPH) collimator that will be used with a fanbeam collimator for high spatial resolution and sensitivity imaging of the striatal region of patients suspected of having Parkinson's disease. The design strategy was to alter an existing commercial pinhole collimator by adding the MPH components while keeping the portion of the collimator that attaches to the head of the gamma-camera. The MPH array consists of nine apertures focused at a common point at the center of the striatal region of the brain with their entrance and exit ports such that no overlapping occurs of their projections on the detector of the gamma-camera. A shutter mechanism is included at the side of the aperture plate towards the detector which will allow opening an additional eight apertures to image with increased sensitivity, but with the projections multiplexed with those of the original nine pinholes. Testing of the material properties of the alloys used in construction of the MPH collimator provided validated values. These were used in a SolidWorks simulation of material deformation due to gravity during imaging to ensure safety and imaging accuracy. The SolidWorks CAD design of the MPH collimator was imported into the GATE Monte Carlo package to simulate brain imaging and to test striatal imaging with the model geometry.

Original language	English (US)
Title of host publication	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781538622827
DOIs	https://doi.org/10.1109/NSSMIC.2017.8533023
State	Published - Nov 12 2018
Event	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Atlanta, United States Duration: Oct 21 2017 → Oct 28 2017

Publication series

Name	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings

Other

Other	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017
Country/Territory	United States
City	Atlanta
Period	10/21/17 → 10/28/17

ASJC Scopus subject areas

Instrumentation
Radiology Nuclear Medicine and imaging
Nuclear and High Energy Physics

Access to Document

10.1109/NSSMIC.2017.8533023

Cite this

He, Y., Konik, A., Beenhouwer, J. D., Fromme, T. J., Lindsay, C., Kalluri, K., Li, X., Momsen, N. C., Furenlid, L. R., & King, M. A. (2018). Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging. In 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings [8533023] (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2017.8533023

Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging. / He, Yulun; Konik, Arda; Beenhouwer, Jan De et al.
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. 8533023 (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

He, Y, Konik, A, Beenhouwer, JD, Fromme, TJ, Lindsay, C, Kalluri, K, Li, X, Momsen, NC, Furenlid, LR & King, MA 2018, Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging. in 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings., 8533023, 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings, Institute of Electrical and Electronics Engineers Inc., 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017, Atlanta, United States, 10/21/17. https://doi.org/10.1109/NSSMIC.2017.8533023

He Y, Konik A, Beenhouwer JD, Fromme TJ, Lindsay C, Kalluri K et al. Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging. In 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc. 2018. 8533023. (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings). doi: 10.1109/NSSMIC.2017.8533023

He, Yulun ; Konik, Arda ; Beenhouwer, Jan De et al. / Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging. 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings).

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title = "Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging",

abstract = "A mechanical design is reported for constructing a multi-pinhole (MPH) collimator that will be used with a fanbeam collimator for high spatial resolution and sensitivity imaging of the striatal region of patients suspected of having Parkinson's disease. The design strategy was to alter an existing commercial pinhole collimator by adding the MPH components while keeping the portion of the collimator that attaches to the head of the gamma-camera. The MPH array consists of nine apertures focused at a common point at the center of the striatal region of the brain with their entrance and exit ports such that no overlapping occurs of their projections on the detector of the gamma-camera. A shutter mechanism is included at the side of the aperture plate towards the detector which will allow opening an additional eight apertures to image with increased sensitivity, but with the projections multiplexed with those of the original nine pinholes. Testing of the material properties of the alloys used in construction of the MPH collimator provided validated values. These were used in a SolidWorks simulation of material deformation due to gravity during imaging to ensure safety and imaging accuracy. The SolidWorks CAD design of the MPH collimator was imported into the GATE Monte Carlo package to simulate brain imaging and to test striatal imaging with the model geometry.",

author = "Yulun He and Arda Konik and Beenhouwer, {Jan De} and Fromme, {Timothy J.} and Clifford Lindsay and Kesava Kalluri and Xin Li and Momsen, {Neil C.} and Furenlid, {Lars R.} and King, {Michael A.}",

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Preliminary Brain SPECT Multi-Pinhole Collimator Mechanical Design for DaTscan Imaging

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