TY - JOUR
T1 - Prediction of noninertial focusing of red blood cells in Poiseuille flow
AU - Hariprasad, Daniel S.
AU - Secomb, Timothy W.
N1 - Publisher Copyright:
© 2015 American Physical Society.
PY - 2015/9/9
Y1 - 2015/9/9
N2 - The motions of a red blood cell in Poiseuille flows in a range of channel widths are simulated using a two-dimensional model. For a range of initial off-centerline distances in a 12-μm channel, cell trajectories converge to a specific off-centerline position and exhibit tank-treading motions. This behavior coexists with initial positions that lead to migration towards the centerline. The predicted off-centerline focusing effect is shown to depend on the curvature of the flow profile and on interactions with both solid boundaries.
AB - The motions of a red blood cell in Poiseuille flows in a range of channel widths are simulated using a two-dimensional model. For a range of initial off-centerline distances in a 12-μm channel, cell trajectories converge to a specific off-centerline position and exhibit tank-treading motions. This behavior coexists with initial positions that lead to migration towards the centerline. The predicted off-centerline focusing effect is shown to depend on the curvature of the flow profile and on interactions with both solid boundaries.
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U2 - 10.1103/PhysRevE.92.033008
DO - 10.1103/PhysRevE.92.033008
M3 - Article
C2 - 26465557
AN - SCOPUS:84942234914
SN - 1539-3755
VL - 92
JO - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
JF - Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
IS - 3
M1 - 033008
ER -