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Precocious Puberty

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Precocious puberty has been a focus of interest for both the pediatric endocrinologist and the primary pediatrician for many years. The development and application of gonadotropin-releasing hormone (GnRH) agonist (GnRHa) therapy to treat central precocious puberty in the 1980s significantly changed our approach to this disorder. More recently, application of molecular biological techniques has led to a better understanding of the intricacies of regulation of gonadotropin and sex-steroid production characteristic of normal pubertal development and provided us with the tools to elucidate etiologies of previously uncharacterized disorders of precocious puberty.

Original languageEnglish (US)
Title of host publicationPediatric Endocrinology
Subtitle of host publicationA Practical Clinical Guide, Fourth Edition
PublisherSpringer Nature
Pages689-720
Number of pages32
ISBN (Electronic)9783031662966
ISBN (Print)9783031662959
DOIs
StatePublished - Jan 1 2024

Keywords

  • Androgen
  • Central precocious puberty (CPP)
  • Estrogen
  • Follicle-stimulating hormone (FSH)
  • GnRH agonist (GnRHa)
  • Gonadotropin-independent precocious puberty
  • Gonadotropin-releasing hormone (GnRH)
  • Luteinizing hormone (LH)
  • Peripheral precocious puberty
  • Precocious puberty

ASJC Scopus subject areas

  • General Medicine

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