Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention

Sara M. Centuori; Carlos Caulin; Julie E. Bauman

doi:10.1007/s11864-021-00848-x

Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention

Sara M. Centuori, Carlos Caulin, Julie E. Bauman

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention.

Original language	English (US)
Article number	52
Journal	Current Treatment Options in Oncology
Volume	22
Issue number	6
DOIs	https://doi.org/10.1007/s11864-021-00848-x
State	Published - Jun 2021

Keywords

Chemoprevention
Head and neck squamous cell carcinoma (HNSCC)
Immunoprevention
Smoking

ASJC Scopus subject areas

Oncology
Pharmacology (medical)

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10.1007/s11864-021-00848-x

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title = "Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention",

abstract = "To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention.",

keywords = "Chemoprevention, Head and neck squamous cell carcinoma (HNSCC), Immunoprevention, Smoking",

author = "Centuori, {Sara M.} and Carlos Caulin and Bauman, {Julie E.}",

note = "Funding Information: HHSN261201200031I, UG1CA242596 Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2021",

month = jun,

doi = "10.1007/s11864-021-00848-x",

language = "English (US)",

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T1 - Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention

AU - Centuori, Sara M.

AU - Caulin, Carlos

AU - Bauman, Julie E.

PY - 2021/6

Y1 - 2021/6

N2 - To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention.

AB - To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently powered randomized trials are needed to reduce the incidence and improve survival. In this review, we recap the challenges encountered in past chemoprevention trials and discuss emerging approaches, with major focus on green chemoprevention, precision prevention, and immunoprevention. As our current depth of knowledge expands in the arena of cancer immunotherapy, the field of immunoprevention is primed for new discoveries and successes in cancer prevention.

KW - Chemoprevention

KW - Head and neck squamous cell carcinoma (HNSCC)

KW - Immunoprevention

KW - Smoking

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Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention

Abstract

Keywords

ASJC Scopus subject areas

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