Preadult Parental Diet Affects Offspring Development and Metabolism in Drosophila melanogaster

Luciano M. Matzkin, Sarah Johnson, Christopher Paight, Therese A. Markow

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

When Drosophila melanogaster larvae are reared on isocaloric diets differing in their amounts of protein relative to sugar, emerging adults exhibit significantly different development times and metabolic pools of protein, glycogen and trigylcerides. In the current study, we show that the influence of larval diet experienced during just one generation extends into the next generation, even when that subsequent generation had been shifted to a standard diet during development. Offspring of flies that were reared on high protein relative to sugar underwent metamorphosis significantly faster, had higher reproductive outputs, and different metabolic pool contents compared to the offspring of adults from low protein relative to sugar diets. In addition, isofemale lines differed in the degree to which parental effects were observed, suggesting a genetic component to the observed transgenerational influences.

Original languageEnglish (US)
Article numbere59530
JournalPloS one
Volume8
Issue number3
DOIs
StatePublished - Mar 26 2013
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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