Potential long-acting contraceptive agents: Esters and ethersof testosterone with α-and/or β-chain branching

J. E. Herz, J. V. Torres, A. Murillo, S. Cruz, A. Shafiee, M. Vosooghi, S. Sotheeswaran, A. A.L. Gunatilaka

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The synthesis of ten esters and two ethers of testosterone (17 β-hydroxyandrost-4-en-3-one) is described. All these possess some form of α-and/or β-substitution in the ester/ether sidechain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males.

Original languageEnglish (US)
Pages (from-to)947-953
Number of pages7
JournalSteroids
Volume46
Issue number6
DOIs
StatePublished - Dec 1985
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Endocrinology
  • Pharmacology
  • Clinical Biochemistry
  • Organic Chemistry

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