Potency, affinity and efficacy of currently available delta opioid agonists

T. H. Kramer; K. D. Wild; G. Toth; P. Davis; V. J. Hruby; T. F. Burks; F. Porreca

Potency, affinity and efficacy of currently available delta opioid agonists

T. H. Kramer, K. D. Wild, G. Toth, P. Davis, V. J. Hruby, T. F. Burks, F. Porreca

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We compared several peptides currently used as selective ligands for δ-opioid receptors with respect to their potency, receptor affinity and transduction efficacy. The compounds differed markedly in terms of receptor affinity, whereas variation in efficacy was minimal.

Original language	English (US)
Title of host publication	New leads in opioid research
Subtitle of host publication	proceedings of the International Narcotics Research Conference. ICS914
Editors	J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
Publisher	Elsevier Science Publishers B.V.
Pages	222
Number of pages	1
ISBN (Print)	044481213X
State	Published - 1990
Event	The International Narcotics Research Conference - Duration: Jul 8 1989 → Jul 13 1989

Publication series

Name	New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Other

Other	The International Narcotics Research Conference
Period	7/8/89 → 7/13/89

ASJC Scopus subject areas

General Medicine

Cite this

Kramer, T. H., Wild, K. D., Toth, G., Davis, P., Hruby, V. J., Burks, T. F., & Porreca, F. (1990). Potency, affinity and efficacy of currently available delta opioid agonists. In J. M. Van Ree, A. H. Mulder, V. M. Wiegant, T. B. Van Wimersma Greidanus, J. M. Van Ree, A. H. Mulder, V. M. Wiegant, & T. B. Van Wimersma Greidanus (Eds.), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914 (pp. 222). (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914). Elsevier Science Publishers B.V..

Potency, affinity and efficacy of currently available delta opioid agonists. / Kramer, T. H.; Wild, K. D.; Toth, G. et al.
New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. ed. / J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus; J.M. Van Ree; A.H. Mulder; V.M. Wiegant; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. p. 222 (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kramer, TH, Wild, KD, Toth, G, Davis, P, Hruby, VJ, Burks, TF & Porreca, F 1990, Potency, affinity and efficacy of currently available delta opioid agonists. in JM Van Ree, AH Mulder, VM Wiegant, TB Van Wimersma Greidanus, JM Van Ree, AH Mulder, VM Wiegant & TB Van Wimersma Greidanus (eds), New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914, Elsevier Science Publishers B.V., pp. 222, The International Narcotics Research Conference, 7/8/89.

Kramer TH, Wild KD, Toth G, Davis P, Hruby VJ, Burks TF et al. Potency, affinity and efficacy of currently available delta opioid agonists. In Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, Van Ree JM, Mulder AH, Wiegant VM, Van Wimersma Greidanus TB, editors, New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. Elsevier Science Publishers B.V. 1990. p. 222. (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

Kramer, T. H. ; Wild, K. D. ; Toth, G. et al. / Potency, affinity and efficacy of currently available delta opioid agonists. New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914. editor / J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus ; J.M. Van Ree ; A.H. Mulder ; V.M. Wiegant ; T.B. Van Wimersma Greidanus. Elsevier Science Publishers B.V., 1990. pp. 222 (New leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914).

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author = "Kramer, {T. H.} and Wild, {K. D.} and G. Toth and P. Davis and Hruby, {V. J.} and Burks, {T. F.} and F. Porreca",

year = "1990",

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AU - Wild, K. D.

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AU - Davis, P.

AU - Hruby, V. J.

AU - Burks, T. F.

AU - Porreca, F.

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BT - New leads in opioid research

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A2 - Wiegant, V.M.

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PB - Elsevier Science Publishers B.V.

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Y2 - 8 July 1989 through 13 July 1989

ER -

Potency, affinity and efficacy of currently available delta opioid agonists

Abstract

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Other

ASJC Scopus subject areas

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