Postural orthostatic tachycardia in a teenager with klinefelter syndrome

Michael R. Hainstock, Nancy E. Gruchala, Nadia Fike, Ricardo A. Samson, Scott E. Klewer, Brent J. Barber

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


To our knowledge this is the first reported case of postural orthostatic tachycardia syndrome (POTS) in a patient with Klinefelter syndrome. We describe a classic clinical presentation of POTS in an adolescent male with Klinefelter syndrome. Although the etiology of POTS appears to be multifactorial, there is a strong female predominance that suggests a genetic basis. Our patient with Klinefelter syndrome may further support a link with POTS to the X chromosome.

Original languageEnglish (US)
Pages (from-to)440-442
Number of pages3
JournalCongenital Heart Disease
Issue number6
StatePublished - 2008


  • Autonomic Dysfunction
  • Klinefelter Syndrome
  • Postural Orthostatic Tachycardia Syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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