Postoperative opioid-free analgesia in elective bowel resection: Changes over time

Ankoor Patel, Aram Rojas, David Samson, Steliana Fakas, Mahir Gachabayov, Jeff L. Xu, Rifat Latifi, Roberto Bergamaschi

Research output: Contribution to journalArticlepeer-review


In the pain management evolution, opioid-free analgesia and multimodal analgesia strategies have emerged as feasible in many surgical settings including colorectal surgery. This was a retrospective cohort study including patients having undergone elective bowel resection between February 2012 and June 2018 aiming to evaluate whether there was reduction in opioid use after implementation of opioid-free analgesia in one medical centre. Trend analysis was conducted using Joinpoint regression employing nine-month intervals. The primary outcome for each interval was the proportion of patients receiving postoperative opioid-free analgesia, defined as forgoing all opioid analgesics after the day of surgery. This study showed a significant increasing trend in opioid-free analgesia in elective bowel resection from 0 to 42.5% over 4.5 years.

Original languageEnglish (US)
Pages (from-to)255-260
Number of pages6
JournalJournal of perioperative practice
Issue number7-8
StatePublished - Jul 2021


  • Postoperative pain / Analgesia / Opioids / Colorectal surgery / Bowel resection

ASJC Scopus subject areas

  • Surgery
  • Medical–Surgical
  • Anesthesiology and Pain Medicine


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