Possible Interactions between Dietary Antioxidants and Chemotherapy

Dan Labriola, Robert Livingston

Research output: Contribution to journalArticlepeer-review

167 Scopus citations


Many patients treat themselves with oral antioxidants and other alternative therapies during chemotherapy, frequently without advising their conventional health care provider. No definitive studies have demonstrated the long-term effects of combining chemotherapeutic agents and oral antioxidants in humans. However, there is sufficient understanding of the mechanisms of action of both chemotherapeutic agents and antioxidants to predict the obvious interactions and to suggest where caution should be exercised with respect to both clinical decisions and study interpretation. This article will describe these potential interactions and areas of concern, based on the available data. It will also suggest several potential courses of action that clinicians may take when patients indicate that they are taking or plan to use alternative therapies.

Original languageEnglish (US)
Pages (from-to)1003-1008
Number of pages6
Issue number7
StatePublished - Jul 1999
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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