Portopulmonary Hypertension

Michael Passarella, Michael B. Fallon, Steven M. Kawut

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


PPHTN is a common complication of portal hypertension in candidates for liver transplantation. The pathophysiology is unknown, and the diagnosis only can be made by pulmonary artery catheterization. Although candidates for liver transplant need to be screened for this complication, the frequency of screening that is necessary in this population is unknown. Novel medical therapies for PPHTN may be emerging, but randomized clinical trials have not focused on this severely compromised patient population. In general, OLT and TIPS should not be performed in patients who have significant PPHTN. Strategies to risk-stratify the patients who may tolerate one or both procedures safely should be investigated.

Original languageEnglish (US)
Pages (from-to)653-663
Number of pages11
JournalClinics in liver disease
Issue number3
StatePublished - Aug 2006

ASJC Scopus subject areas

  • Hepatology


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