Portopulmonary Hypertension

Michael Passarella; Michael B. Fallon; Steven M. Kawut

doi:10.1016/j.cld.2006.08.023

Portopulmonary Hypertension

Michael Passarella, Michael B. Fallon, Steven M. Kawut

Research output: Contribution to journal › Review article › peer-review

17 Scopus citations

Abstract

PPHTN is a common complication of portal hypertension in candidates for liver transplantation. The pathophysiology is unknown, and the diagnosis only can be made by pulmonary artery catheterization. Although candidates for liver transplant need to be screened for this complication, the frequency of screening that is necessary in this population is unknown. Novel medical therapies for PPHTN may be emerging, but randomized clinical trials have not focused on this severely compromised patient population. In general, OLT and TIPS should not be performed in patients who have significant PPHTN. Strategies to risk-stratify the patients who may tolerate one or both procedures safely should be investigated.

Original language	English (US)
Pages (from-to)	653-663
Number of pages	11
Journal	Clinics in liver disease
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/j.cld.2006.08.023
State	Published - Aug 2006
Externally published	Yes

ASJC Scopus subject areas

Hepatology

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10.1016/j.cld.2006.08.023

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title = "Portopulmonary Hypertension",

abstract = "PPHTN is a common complication of portal hypertension in candidates for liver transplantation. The pathophysiology is unknown, and the diagnosis only can be made by pulmonary artery catheterization. Although candidates for liver transplant need to be screened for this complication, the frequency of screening that is necessary in this population is unknown. Novel medical therapies for PPHTN may be emerging, but randomized clinical trials have not focused on this severely compromised patient population. In general, OLT and TIPS should not be performed in patients who have significant PPHTN. Strategies to risk-stratify the patients who may tolerate one or both procedures safely should be investigated.",

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year = "2006",

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AU - Passarella, Michael

AU - Fallon, Michael B.

AU - Kawut, Steven M.

PY - 2006/8

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N2 - PPHTN is a common complication of portal hypertension in candidates for liver transplantation. The pathophysiology is unknown, and the diagnosis only can be made by pulmonary artery catheterization. Although candidates for liver transplant need to be screened for this complication, the frequency of screening that is necessary in this population is unknown. Novel medical therapies for PPHTN may be emerging, but randomized clinical trials have not focused on this severely compromised patient population. In general, OLT and TIPS should not be performed in patients who have significant PPHTN. Strategies to risk-stratify the patients who may tolerate one or both procedures safely should be investigated.

AB - PPHTN is a common complication of portal hypertension in candidates for liver transplantation. The pathophysiology is unknown, and the diagnosis only can be made by pulmonary artery catheterization. Although candidates for liver transplant need to be screened for this complication, the frequency of screening that is necessary in this population is unknown. Novel medical therapies for PPHTN may be emerging, but randomized clinical trials have not focused on this severely compromised patient population. In general, OLT and TIPS should not be performed in patients who have significant PPHTN. Strategies to risk-stratify the patients who may tolerate one or both procedures safely should be investigated.

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AN - SCOPUS:33845293378

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SP - 653

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JO - Clinics in liver disease

JF - Clinics in liver disease

IS - 3

ER -

Portopulmonary Hypertension

Abstract

ASJC Scopus subject areas

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