Polymeric gastrointestinal MR contrast agents

Colin Tilcock; Evan C. Unger; Quet Fah Ahkong; Tom Fritz; Seymour H. Koenig; Rodney D. Brown

doi:10.1002/jmri.1880010411

Polymeric gastrointestinal MR contrast agents

Colin Tilcock, Evan C. Unger, Quet Fah Ahkong, Tom Fritz, Seymour H. Koenig, Rodney D. Brown

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Combining either paramagnetic (gadolinium chelatea) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.

Original language	English (US)
Pages (from-to)	463-467
Number of pages	5
Journal	Journal of Magnetic Resonance Imaging
Volume	1
Issue number	4
DOIs	https://doi.org/10.1002/jmri.1880010411
State	Published - 1991
Externally published	Yes

Keywords

Contrast enhancement
Contrast media, experimental studies
Gadolinium
Gastrointestinal tract, MR studies, 70.1214
Iron
Relaxometry

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/jmri.1880010411

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title = "Polymeric gastrointestinal MR contrast agents",

abstract = "Combining either paramagnetic (gadolinium chelatea) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.",

keywords = "Contrast enhancement, Contrast media, experimental studies, Gadolinium, Gastrointestinal tract, MR studies, 70.1214, Iron, Relaxometry",

author = "Colin Tilcock and Unger, {Evan C.} and Ahkong, {Quet Fah} and Tom Fritz and Koenig, {Seymour H.} and Brown, {Rodney D.}",

year = "1991",

doi = "10.1002/jmri.1880010411",

language = "English (US)",

volume = "1",

pages = "463--467",

journal = "Journal of Magnetic Resonance Imaging",

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publisher = "John Wiley and Sons Inc.",

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}

TY - JOUR

T1 - Polymeric gastrointestinal MR contrast agents

AU - Tilcock, Colin

AU - Unger, Evan C.

AU - Ahkong, Quet Fah

AU - Fritz, Tom

AU - Koenig, Seymour H.

AU - Brown, Rodney D.

PY - 1991

Y1 - 1991

N2 - Combining either paramagnetic (gadolinium chelatea) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.

AB - Combining either paramagnetic (gadolinium chelatea) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.

KW - Contrast enhancement

KW - Contrast media, experimental studies

KW - Gadolinium

KW - Gastrointestinal tract, MR studies, 70.1214

KW - Iron

KW - Relaxometry

UR - http://www.scopus.com/inward/record.url?scp=0026183443&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026183443&partnerID=8YFLogxK

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DO - 10.1002/jmri.1880010411

M3 - Article

C2 - 1790369

AN - SCOPUS:0026183443

SN - 1053-1807

VL - 1

SP - 463

EP - 467

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

IS - 4

ER -

Polymeric gastrointestinal MR contrast agents

Abstract

Keywords

ASJC Scopus subject areas

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