Abstract
The development of cheap versatile plastics has caused a significant social and economic impact worldwide. Ironically, characteristics that make plastics desirable have also allowed them to leach out of our products, silently enter our bodies and potentially increase disease risk. Bisphenol A and phthalates are examples of widely-used, well-characterized endocrine disrupting plasticizers. Originally considered to be safe following classical high dose studies, contemporary studies increasingly reveal that BPA and phthalates are detrimental at levels within the range of estimated human exposures. This chapter summarizes classical and contemporary evidence documenting the interactions of these plasticizers with the female reproductive tract.
Original language | English (US) |
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Title of host publication | Encyclopedia of Reproduction |
Publisher | Elsevier |
Pages | 707-713 |
Number of pages | 7 |
ISBN (Electronic) | 9780128151457 |
DOIs | |
State | Published - Jan 1 2018 |
Keywords
- Bisphenol a
- Embryo
- Endocrine disruptor
- Endometrium
- Hormones
- Infertility
- Oocyte
- Ovary
- Phthalate
- Placenta
- Plastic
- Pregnancy
- Steroidogenesis
- Uterus
ASJC Scopus subject areas
- General Medicine