Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation

Stavros P. Ionides; Marc G. Weiss; Margarite Angelopoulos; Thomas F. Myers; Robert J. Handa

doi:10.1016/S0022-3476(94)70136-9

Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation

Stavros P. Ionides
, Marc G. Weiss
, Margarite Angelopoulos
, Thomas F. Myers
, Robert J. Handa

Basic Medical Sciences, Phoenix

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

We evaluated the effects of pancuronium and opiates on plasma β-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in β-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced β-endorphin concentrations by approximately 60%. (J PEDIATR 1994;125:113-6)

Original language	English (US)
Pages (from-to)	113-116
Number of pages	4
Journal	Journal of Pediatrics
Volume	125
Issue number	1
DOIs	https://doi.org/10.1016/S0022-3476(94)70136-9
State	Published - 1994

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/S0022-3476(94)70136-9

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title = "Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation",

abstract = "We evaluated the effects of pancuronium and opiates on plasma β-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in β-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced β-endorphin concentrations by approximately 60\%. (J PEDIATR 1994;125:113-6)",

author = "Ionides, \{Stavros P.\} and Weiss, \{Marc G.\} and Margarite Angelopoulos and Myers, \{Thomas F.\} and Handa, \{Robert J.\}",

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AU - Ionides, Stavros P.

AU - Weiss, Marc G.

AU - Angelopoulos, Margarite

AU - Myers, Thomas F.

AU - Handa, Robert J.

PY - 1994

Y1 - 1994

N2 - We evaluated the effects of pancuronium and opiates on plasma β-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in β-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced β-endorphin concentrations by approximately 60%. (J PEDIATR 1994;125:113-6)

AB - We evaluated the effects of pancuronium and opiates on plasma β-endorphin concentrations in 25 infants supported by mechanical ventilation. Infants receiving opiate were randomly assigned to receive either fentanyl or morphine. There was no change in β-endorphin concentrations after administration of pancuronium, whereas both fentanyl and morphine reduced β-endorphin concentrations by approximately 60%. (J PEDIATR 1994;125:113-6)

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Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation

Abstract

ASJC Scopus subject areas

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