Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Philip E. Castle; Mark Sadorra; Francisco Garcia; E. Blair Holladay; Janet Kornegay

doi:10.1128/JCM.01305-06

Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Philip E. Castle
, Mark Sadorra
, Francisco Garcia
, E. Blair Holladay
, Janet Kornegay

Health Promotion Sciences

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (P_Trend < 0.0005) and histologic diagnoses (P_Trend < 0.0005).

Original language	English (US)
Pages (from-to)	3915-3917
Number of pages	3
Journal	Journal of clinical microbiology
Volume	44
Issue number	11
DOIs	https://doi.org/10.1128/JCM.01305-06
State	Published - Nov 2006

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/JCM.01305-06

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abstract = "We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (PTrend < 0.0005) and histologic diagnoses (PTrend < 0.0005).",

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AU - Holladay, E. Blair

AU - Kornegay, Janet

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Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Abstract

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