Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Philip E. Castle; Mark Sadorra; Francisco Garcia; E. Blair Holladay; Janet Kornegay

doi:10.1128/JCM.01305-06

Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Philip E. Castle, Mark Sadorra, Francisco Garcia, E. Blair Holladay, Janet Kornegay

Health Promotion Sciences

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (P_Trend < 0.0005) and histologic diagnoses (P_Trend < 0.0005).

Original language	English (US)
Pages (from-to)	3915-3917
Number of pages	3
Journal	Journal of clinical microbiology
Volume	44
Issue number	11
DOIs	https://doi.org/10.1128/JCM.01305-06
State	Published - Nov 2006

ASJC Scopus subject areas

Microbiology (medical)

Access to Document

10.1128/JCM.01305-06

Cite this

@article{a41dfcafda50431d930d52bd5b67a011,

title = "Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology",

abstract = "We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (PTrend < 0.0005) and histologic diagnoses (PTrend < 0.0005).",

author = "Castle, {Philip E.} and Mark Sadorra and Francisco Garcia and Holladay, {E. Blair} and Janet Kornegay",

year = "2006",

month = nov,

doi = "10.1128/JCM.01305-06",

language = "English (US)",

volume = "44",

pages = "3915--3917",

journal = "Journal of clinical microbiology",

issn = "0095-1137",

publisher = "American Society for Microbiology",

number = "11",

}

TY - JOUR

T1 - Pilot study of a commercialized human papillomavirus (HPV) genotyping assay

T2 - Comparison of HPV risk group to cytology and histology

AU - Castle, Philip E.

AU - Sadorra, Mark

AU - Garcia, Francisco

AU - Holladay, E. Blair

AU - Kornegay, Janet

PY - 2006/11

Y1 - 2006/11

N2 - We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (PTrend < 0.0005) and histologic diagnoses (PTrend < 0.0005).

AB - We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noacaranogenic types > negative specimens) with increasing severities of cytologic interpretations (PTrend < 0.0005) and histologic diagnoses (PTrend < 0.0005).

UR - http://www.scopus.com/inward/record.url?scp=33750936268&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750936268&partnerID=8YFLogxK

U2 - 10.1128/JCM.01305-06

DO - 10.1128/JCM.01305-06

M3 - Article

C2 - 16971652

AN - SCOPUS:33750936268

SN - 0095-1137

VL - 44

SP - 3915

EP - 3917

JO - Journal of clinical microbiology

JF - Journal of clinical microbiology

IS - 11

ER -

Pilot study of a commercialized human papillomavirus (HPV) genotyping assay: Comparison of HPV risk group to cytology and histology

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this