Phototriggering of geometric dendrimer disassembly: An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers

Michael L. Szalai; Dominic V. McGrath

doi:10.1016/j.tet.2004.06.078

Phototriggering of geometric dendrimer disassembly: An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers

Michael L. Szalai, Dominic V. McGrath

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Dendrimers capable of phototriggered disassembly were prepared up to the second-generation using an improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. It was found that disassembly proceeds to 75-80% completion after 2 h of irradiation at 310 nm for all molecules studied. The lack of complete reaction is attributed to an inefficient photochemical deprotection process rather than the disassembly itself.

Original language	English (US)
Pages (from-to)	7261-7266
Number of pages	6
Journal	Tetrahedron
Volume	60
Issue number	34
DOIs	https://doi.org/10.1016/j.tet.2004.06.078
State	Published - Aug 16 2004

Keywords

Dendrimers
Disassembly
Tetrahydrofuran

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2004.06.078

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title = "Phototriggering of geometric dendrimer disassembly: An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers",

abstract = "Dendrimers capable of phototriggered disassembly were prepared up to the second-generation using an improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. It was found that disassembly proceeds to 75-80% completion after 2 h of irradiation at 310 nm for all molecules studied. The lack of complete reaction is attributed to an inefficient photochemical deprotection process rather than the disassembly itself.",

keywords = "Dendrimers, Disassembly, Tetrahydrofuran",

author = "Szalai, {Michael L.} and McGrath, {Dominic V.}",

note = "Funding Information: This work was supported by the National Science Foundation (CHE-0213537).",

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T2 - An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers

AU - Szalai, Michael L.

AU - McGrath, Dominic V.

N1 - Funding Information: This work was supported by the National Science Foundation (CHE-0213537).

PY - 2004/8/16

Y1 - 2004/8/16

N2 - Dendrimers capable of phototriggered disassembly were prepared up to the second-generation using an improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. It was found that disassembly proceeds to 75-80% completion after 2 h of irradiation at 310 nm for all molecules studied. The lack of complete reaction is attributed to an inefficient photochemical deprotection process rather than the disassembly itself.

AB - Dendrimers capable of phototriggered disassembly were prepared up to the second-generation using an improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers. It was found that disassembly proceeds to 75-80% completion after 2 h of irradiation at 310 nm for all molecules studied. The lack of complete reaction is attributed to an inefficient photochemical deprotection process rather than the disassembly itself.

KW - Dendrimers

KW - Disassembly

KW - Tetrahydrofuran

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IS - 34

ER -

Phototriggering of geometric dendrimer disassembly: An improved synthesis of 2,4-bis(hydroxymethyl)phenol based dendrimers

Abstract

Keywords

ASJC Scopus subject areas

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