Abstract
A photoredox catalytic asymmetric method has been established for the installation of both aliphatic and aromatic side chains and the introduction of deuterium into the chiral methyleneoxazolidinone simultaneously. Efficient coupling of readily available boronic acids with the chiral auxiliary delivers structurally diverse α-deuterated α-amino acid derivatives with a high level of diastereoselectivity and deuteration.
Original language | English (US) |
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Pages (from-to) | 4745-4749 |
Number of pages | 5 |
Journal | Organic Letters |
Volume | 25 |
Issue number | 25 |
DOIs | |
State | Published - Jun 30 2023 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry