Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects

A. Shah; J. Lettieri; D. Nix; J. Wilton; A. H. Heller

doi:10.1128/AAC.39.4.1003

Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects

A. Shah, J. Lettieri, D. Nix, J. Wilton, A. H. Heller

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

The effects of age and gender on the pharmacokinetics of high-dose intravenous ciprofloxacin in a healthy volunteer study were investigated. Plasma ciprofloxacin concentrations were higher in the elderly than in the young, and the pharmacokinetic parameters were not significantly different between the genders. Ciprofloxacin was well tolerated, with the majority of adverse events related to local reactions at the IV site.

Original language	English (US)
Pages (from-to)	1003-1006
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	39
Issue number	4
DOIs	https://doi.org/10.1128/AAC.39.4.1003
State	Published - 1995

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.39.4.1003

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abstract = "The effects of age and gender on the pharmacokinetics of high-dose intravenous ciprofloxacin in a healthy volunteer study were investigated. Plasma ciprofloxacin concentrations were higher in the elderly than in the young, and the pharmacokinetic parameters were not significantly different between the genders. Ciprofloxacin was well tolerated, with the majority of adverse events related to local reactions at the IV site.",

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AU - Wilton, J.

AU - Heller, A. H.

PY - 1995

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AB - The effects of age and gender on the pharmacokinetics of high-dose intravenous ciprofloxacin in a healthy volunteer study were investigated. Plasma ciprofloxacin concentrations were higher in the elderly than in the young, and the pharmacokinetic parameters were not significantly different between the genders. Ciprofloxacin was well tolerated, with the majority of adverse events related to local reactions at the IV site.

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Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects

Abstract

ASJC Scopus subject areas

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