Pharmacogenetics: Ethical issues and policy options

Allen Buchanan, Andrea Califano, Jeffrey Kahn, Elizabeth McPherson, John Robertson, Baruch Brody

Research output: Contribution to journalArticlepeer-review

70 Scopus citations

Abstract

Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. Before the benefits of pharmacogenetics can be realized, the ethical issues that arise in research and clinical application of pharmacogenetic technologies must be addressed. The ethical issues raised by pharmacogenetics can be addressed under six headings: (1) regulatory oversight, (2) confidentiality and privacy, (3) informed consent, (4) availability of drugs, (5) access, and (6) clinicians' changing responsibilities in the era of pharmacogenetic medicine. We analyze each of these categories of ethical issues and provide policy approaches for addressing them.

Original languageEnglish (US)
Pages (from-to)1-15
Number of pages15
JournalKennedy Institute of Ethics Journal
Volume12
Issue number1
DOIs
StatePublished - Mar 2002

ASJC Scopus subject areas

  • Issues, ethics and legal aspects
  • Health(social science)
  • Health Policy
  • History and Philosophy of Science

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