TY - JOUR
T1 - Pharmacogenetic challenges for the health care system
AU - Robertson, John A.
AU - Brody, Baruch
AU - Buchanan, Allen
AU - Kahn, Jeffrey
AU - McPherson, Elizabeth
PY - 2002
Y1 - 2002
N2 - Pharmacogenetics-the effect of genotype on drug response-holds the promise of safer and more effective drug therapy. Genetic tests would be routinely given to patients prior to prescription of a drug, with therapeutic decisions based on the patient's drug-response profile. This paper examines the operational changes and the ethical, legal, and policy challenges that pharmacogenetic medicine poses for key actors in the health care system. Adaptation by drug companies, regulatory agencies, physicians, patients, insurers, and public funding agencies will be necessary to integrate pharmacogenetic medicine into health care.
AB - Pharmacogenetics-the effect of genotype on drug response-holds the promise of safer and more effective drug therapy. Genetic tests would be routinely given to patients prior to prescription of a drug, with therapeutic decisions based on the patient's drug-response profile. This paper examines the operational changes and the ethical, legal, and policy challenges that pharmacogenetic medicine poses for key actors in the health care system. Adaptation by drug companies, regulatory agencies, physicians, patients, insurers, and public funding agencies will be necessary to integrate pharmacogenetic medicine into health care.
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U2 - 10.1377/hlthaff.21.4.155
DO - 10.1377/hlthaff.21.4.155
M3 - Article
C2 - 12117126
AN - SCOPUS:0036635332
SN - 0278-2715
VL - 21
SP - 155
EP - 167
JO - Health Affairs
JF - Health Affairs
IS - 4
ER -