Phage Application for the Protection from Acute Hepatopancreatic Necrosis Disease (AHPND) in Penaeus vannamei

Jin Woo Jun; Jee Eun Han; Sib Sankar Giri; Kathy F.J. Tang; Xiaohui Zhou; Luis Fernando Aranguren; Hyoun Joong Kim; Saekil Yun; Cheng Chi; Sang Guen Kim; Se Chang Park

doi:10.1007/s12088-017-0694-9

Phage Application for the Protection from Acute Hepatopancreatic Necrosis Disease (AHPND) in Penaeus vannamei

Jin Woo Jun
, Jee Eun Han
, Sib Sankar Giri
, Kathy F.J. Tang
, Xiaohui Zhou
, Luis Fernando Aranguren
, Hyoun Joong Kim
, Saekil Yun
, Cheng Chi
, Sang Guen Kim
, Se Chang Park

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Abstract

Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus has been one of the most problematic diseases in marine shrimp aquaculture throughout Southeast Asia and Latin America. To evaluate the effectiveness of a bacteriophage (phage) treatment for AHPND, a series of bioassays were carried out in a marine shrimp (Penaeus vannamei) model using an AHPND-V. parahaemolyticus strain that is highly pathogenic to shrimp. We monitored the mortality and histopathological changes during phage treatment. Shrimps treated with phage prophylaxis and phage therapy displayed significant protection from AHPND and survived a lethal bacterial challenge.

Original language	English (US)
Pages (from-to)	114-117
Number of pages	4
Journal	Indian Journal of Microbiology
Volume	58
Issue number	1
DOIs	https://doi.org/10.1007/s12088-017-0694-9
State	Published - Mar 1 2018

Keywords

Acute hepatopancreatic necrosis disease (AHPND)
Phage prophylaxis
Phage therapy
Vibrio parahaemolyticus

ASJC Scopus subject areas

Microbiology

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10.1007/s12088-017-0694-9

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title = "Phage Application for the Protection from Acute Hepatopancreatic Necrosis Disease (AHPND) in Penaeus vannamei",

abstract = "Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus has been one of the most problematic diseases in marine shrimp aquaculture throughout Southeast Asia and Latin America. To evaluate the effectiveness of a bacteriophage (phage) treatment for AHPND, a series of bioassays were carried out in a marine shrimp (Penaeus vannamei) model using an AHPND-V. parahaemolyticus strain that is highly pathogenic to shrimp. We monitored the mortality and histopathological changes during phage treatment. Shrimps treated with phage prophylaxis and phage therapy displayed significant protection from AHPND and survived a lethal bacterial challenge.",

keywords = "Acute hepatopancreatic necrosis disease (AHPND), Phage prophylaxis, Phage therapy, Vibrio parahaemolyticus",

author = "Jun, \{Jin Woo\} and Han, \{Jee Eun\} and Giri, \{Sib Sankar\} and Tang, \{Kathy F.J.\} and Xiaohui Zhou and Aranguren, \{Luis Fernando\} and Kim, \{Hyoun Joong\} and Saekil Yun and Cheng Chi and Kim, \{Sang Guen\} and Park, \{Se Chang\}",

note = "Publisher Copyright: {\textcopyright} 2017, Association of Microbiologists of India.",

year = "2018",

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doi = "10.1007/s12088-017-0694-9",

language = "English (US)",

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AU - Jun, Jin Woo

AU - Han, Jee Eun

AU - Giri, Sib Sankar

AU - Tang, Kathy F.J.

AU - Zhou, Xiaohui

AU - Aranguren, Luis Fernando

AU - Kim, Hyoun Joong

AU - Yun, Saekil

AU - Chi, Cheng

AU - Kim, Sang Guen

AU - Park, Se Chang

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus has been one of the most problematic diseases in marine shrimp aquaculture throughout Southeast Asia and Latin America. To evaluate the effectiveness of a bacteriophage (phage) treatment for AHPND, a series of bioassays were carried out in a marine shrimp (Penaeus vannamei) model using an AHPND-V. parahaemolyticus strain that is highly pathogenic to shrimp. We monitored the mortality and histopathological changes during phage treatment. Shrimps treated with phage prophylaxis and phage therapy displayed significant protection from AHPND and survived a lethal bacterial challenge.

AB - Acute hepatopancreatic necrosis disease (AHPND) caused by Vibrio parahaemolyticus has been one of the most problematic diseases in marine shrimp aquaculture throughout Southeast Asia and Latin America. To evaluate the effectiveness of a bacteriophage (phage) treatment for AHPND, a series of bioassays were carried out in a marine shrimp (Penaeus vannamei) model using an AHPND-V. parahaemolyticus strain that is highly pathogenic to shrimp. We monitored the mortality and histopathological changes during phage treatment. Shrimps treated with phage prophylaxis and phage therapy displayed significant protection from AHPND and survived a lethal bacterial challenge.

KW - Acute hepatopancreatic necrosis disease (AHPND)

KW - Phage prophylaxis

KW - Phage therapy

KW - Vibrio parahaemolyticus

UR - https://www.scopus.com/pages/publications/85038107111

UR - https://www.scopus.com/pages/publications/85038107111#tab=citedBy

U2 - 10.1007/s12088-017-0694-9

DO - 10.1007/s12088-017-0694-9

M3 - Article

AN - SCOPUS:85038107111

SN - 0046-8991

VL - 58

SP - 114

EP - 117

JO - Indian Journal of Microbiology

JF - Indian Journal of Microbiology

IS - 1

ER -

Phage Application for the Protection from Acute Hepatopancreatic Necrosis Disease (AHPND) in Penaeus vannamei

Abstract

Keywords

ASJC Scopus subject areas

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