Perspectives on Spect

H. H. Barrett

Research output: Contribution to journalArticlepeer-review


Single-photon emission computed tomography (SPECT) is an inverse problem in which one wants to determine the distribution of a radionuclide from a set of measured projections. Like most inverse problems, it is illposed and does not admit of an exact solution. In this paper we review various methods from the literature on inverse problems that are applicable to SPECT. Topics considered include the discrete representation of continuous objects, the intrinsic dimensionality of an object, null functions, the role of prior information, and various reconstruction principles, including maximum likelihood, least squares, and Bayesian methods.

Original languageEnglish (US)
Pages (from-to)265-269
Number of pages5
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jan 1 1986

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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