TY - JOUR
T1 - Performance of the Super Modified Simplex
AU - Routh, M. W.
AU - Swartz, P. A.
AU - Denton, M. B.
PY - 1977/8/1
Y1 - 1977/8/1
N2 - A new, improved simplex optimization procedure has been developed which significantly increases the utility, reliability, and efficiency of current state-of-the-art simplicial methods in the presence of random response fluctuations. Comparison of this improved procedure, the Super Modified Simplex (SMS), with several variations of the modified simplex approach utilizing an interactively computer-controlled flame spectrophotometer reveals its inherent superiority In rapidly and efficiently conforming to multidimensional response surface topography. Data are presented which indicate fewer simplices and data points, as well as a reduction in experimental time results when the SMS procedure is employed. Moreover, failure to satisfactorily locate the optimum in the presence of noise due to premature diminuation of the simplex, adherence to false ridges, or inability to accurately home in on the optimum is minimized.
AB - A new, improved simplex optimization procedure has been developed which significantly increases the utility, reliability, and efficiency of current state-of-the-art simplicial methods in the presence of random response fluctuations. Comparison of this improved procedure, the Super Modified Simplex (SMS), with several variations of the modified simplex approach utilizing an interactively computer-controlled flame spectrophotometer reveals its inherent superiority In rapidly and efficiently conforming to multidimensional response surface topography. Data are presented which indicate fewer simplices and data points, as well as a reduction in experimental time results when the SMS procedure is employed. Moreover, failure to satisfactorily locate the optimum in the presence of noise due to premature diminuation of the simplex, adherence to false ridges, or inability to accurately home in on the optimum is minimized.
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U2 - 10.1021/ac50017a033
DO - 10.1021/ac50017a033
M3 - Article
AN - SCOPUS:33847089535
SN - 0003-2700
VL - 49
SP - 1422
EP - 1428
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 9
ER -