Pattern recognition for rapid T2 mapping with stimulated echo compensation

Chuan Huang, Maria I. Altbach, Georges El Fakhri

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to provide accurate T2 estimates with indirect echo compensation. However, the iterative nonlinear least square fitting is computationally expensive and the T2 map generation time is long. In this work, we present a pattern recognition T2 mapping technique based on the SEPG model that can be performed with a single pre-computed dictionary for any arbitrary echo spacing. Almost identical T2 and B1 maps were obtained from in vivo data using the proposed technique compared to conventional iterative nonlinear least square fitting, while the computation time was reduced by more than 14-fold.

Original languageEnglish (US)
Pages (from-to)969-974
Number of pages6
JournalMagnetic Resonance Imaging
Issue number7
StatePublished - Sep 2014


  • Indirect echoes
  • MR parameter
  • Quantitative MRI
  • Slice imperfection
  • Stimulated echoes
  • T2 mapping

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging


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