PARP-1 hyperactivation and reciprocal elevations in intracellular Ca²⁺ during ROS-induced nonapoptotic cell death

Keyphrases

• Hyperactivity 100%
• PARP Inhibitor (PARPi) 100%
• Non-apoptotic Cell Death 100%
• Nicotinamide Adenine Dinucleotide (NAD+) 16%
• Species-dependent 16%
• Chelation 16%
• Reactive Oxygen Species Production 16%
• Poly(ADP-ribose) Polymers 8%
• Pathological Conditions 8%
• Renal Ischemia-reperfusion Injury 8%
• Apoptosis-inducing Factor 8%
• HK-2 Cells 8%
• HK-2 8%
• BAPTA 8%
• PJ34 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Nicotinamide Adenine Dinucleotide Adenosine Diphosphate Ribosyltransferase 1 100%
• Trometamol 41%
• Nicotinamide Adenine Dinucleotide 16%
• N (5,6 Dihydro 6 Oxo 2 Phenanthridinyl) 2 Dimethylaminoacetamide 8%
• Reperfusion Injury 8%
• Kidney Ischemia 8%
• Ethylene Glycol 1,2 Bis(2 Aminophenyl) Ether N,n,n',n' Tetraacetic Acid 8%
• Apoptosis Inducing Factor 8%