Abstract
Parental histories of childhood respiratory trouble (CRT) were examined as risk factors for lower respiratory tract illnesses in healthy infants enrolled in the Children's Respiratory Study, Tucson, Arizona. A parental history of childhood respiratory trouble before age 16 was a risk factor for infantile lower respiratory tract illnesses (LRIs). Early age of onset of the parental CRT and those illnesses described as asthma or bronchiolitis showed the greatest risk: odds ratio = 2.8, P < 0.05. After controlling for known and suspected confounders, a parental history of CRT described as asthma or bronchiolitis with onset before age 3 was associated with wheezing LRls in their children, with an odds ratio of 2.6, P < 0.05. A parental history of CRT described as bronchitis/croup was associated with nonwheezing LRls in their children: odds ratio = 2.2, P < 0.05. These findings suggest a familial component to childhood respiratory trouble which may have a hereditary basis. Pediatr Pulmonol. 1993; 16:275–280. © 1993 Wiley‐Liss, Inc.
Original language | English (US) |
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Pages (from-to) | 275-280 |
Number of pages | 6 |
Journal | Pediatric pulmonology |
Volume | 16 |
Issue number | 5 |
DOIs | |
State | Published - Nov 1993 |
Keywords
- Parental asthma
- bronchiolitis
- bronchitis
- croup
- non‐wheezing lower respiratory illness
- wheezing
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Pulmonary and Respiratory Medicine