Parasite potpourri: Toxoplasma gondii lineage tracing in vivo

Research output: Contribution to journalShort surveypeer-review


Using a CRISPR/Cas9-based method, Wincott et al. generated a stable, complex Toxoplasma gondii population composed of 96 barcoded clonal lineages. By tracking the population structure in vivo, they determine that – contrary to expectations – the pathway to infecting the brain is widely permissive for T. gondii.

Original languageEnglish (US)
Pages (from-to)1026-1027
Number of pages2
JournalTrends in Parasitology
Issue number12
StatePublished - Dec 2022
Externally publishedYes


  • Toxoplasma gondii
  • blood–brain barrier
  • dissemination
  • genetic bottleneck
  • molecular barcode

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases


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