Outcomes of Repeat Boston Type 1 Keratoprosthesis Implantation

Sumayya Ahmad, Priya M. Mathews, Divya Srikumaran, Anthony J. Aldave, Tamara Lenis, James V. Aquavella, Sadeer B. Hannush, Michael Belin, Esen Karamursel Akpek

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Purpose To describe the outcomes and prognostic characteristics of patients who had a repeat Boston type 1 keratoprosthesis (KPro) implantation. Design Retrospective case series. Methods setting: Data regarding preoperative clinical and demographic characteristics and postoperative course during initial and repeat KPro placement were collected at multiple centers across the country. patients: Forty-eight eyes underwent explantation of KPro owing to complications between September 2003 and August 2014 at 5 participating tertiary eye care centers in the United States. Of those, 36 eyes that received a subsequent replacement device were included. main outcome measures: Visual acuity (VA) outcomes and postoperative complications. Results Ocular surface disease was significantly more common in eyes that required a device explantation, compared to those that retained the device (P <.001). Sixty-seven percent of eyes (24/36) achieved VA ≥20/200 vision after the repeat KPro. The probability of these 24 eyes maintaining VA ≥20/200 after the repeat KPro was 87% at 1 year and 75% at 2 years. Predictors of the ability to maintain vision ≥20/200 following surgery were a better last-recorded vision before explantation (P =.0002) and better vision immediately after repeat KPro (P <.001). Conclusion Ocular surface disease and its complications were associated with more frequent device removal. In these patients, repeat KPro resulted in restoration of vision. A reasonable visual acuity prior to device removal was associated with favorable long-term postoperative visual acuity and retention.

Original languageEnglish (US)
Pages (from-to)181-187.e1
JournalAmerican Journal of Ophthalmology
StatePublished - Jan 1 2016

ASJC Scopus subject areas

  • Ophthalmology


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