Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis

Michael J. Wagner; Seth M. Pollack; Lee D. Cranmer; Matthew J. Thompson; Shannon Maxwell; Stephanie Wright; Ali R. Khaki; Margaret M. Madeleine; Petros Grivas; Nicole M. Kuderer; Gary H. Lyman; Elizabeth T. Loggers

doi:10.1080/07357907.2021.1903914

Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis

Michael J. Wagner
, Seth M. Pollack
, Lee D. Cranmer
, Matthew J. Thompson
, Shannon Maxwell
, Stephanie Wright
, Ali R. Khaki
, Margaret M. Madeleine
, Petros Grivas
, Nicole M. Kuderer
, Gary H. Lyman
, Elizabeth T. Loggers

Cancer Center

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24–69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6–41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20–62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.

Original language	English (US)
Pages (from-to)	315-320
Number of pages	6
Journal	Cancer Investigation
Volume	39
Issue number	4
DOIs	https://doi.org/10.1080/07357907.2021.1903914
State	Published - 2021

Keywords

COVID-19
Sarcoma
cohort Study

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1080/07357907.2021.1903914

Cite this

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title = "Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis",

abstract = "Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24–69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6–41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20–62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.",

keywords = "COVID-19, Sarcoma, cohort Study",

author = "Wagner, \{Michael J.\} and Pollack, \{Seth M.\} and Cranmer, \{Lee D.\} and Thompson, \{Matthew J.\} and Shannon Maxwell and Stephanie Wright and Khaki, \{Ali R.\} and Madeleine, \{Margaret M.\} and Petros Grivas and Kuderer, \{Nicole M.\} and Lyman, \{Gary H.\} and Loggers, \{Elizabeth T.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Taylor \& Francis Group, LLC.",

year = "2021",

doi = "10.1080/07357907.2021.1903914",

language = "English (US)",

volume = "39",

pages = "315--320",

journal = "Cancer Investigation",

issn = "0735-7907",

publisher = "Taylor \& Francis Group LLC Philadelphia",

number = "4",

}

TY - JOUR

T1 - Outcomes of Patients with Sarcoma and COVID-19 Infection

T2 - A Single Institution Cohort Analysis

AU - Wagner, Michael J.

AU - Pollack, Seth M.

AU - Cranmer, Lee D.

AU - Thompson, Matthew J.

AU - Maxwell, Shannon

AU - Wright, Stephanie

AU - Khaki, Ali R.

AU - Madeleine, Margaret M.

AU - Grivas, Petros

AU - Kuderer, Nicole M.

AU - Lyman, Gary H.

AU - Loggers, Elizabeth T.

PY - 2021

Y1 - 2021

N2 - Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24–69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6–41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20–62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.

AB - Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24–69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6–41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20–62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.

KW - COVID-19

KW - Sarcoma

KW - cohort Study

UR - https://www.scopus.com/pages/publications/85103238611

UR - https://www.scopus.com/pages/publications/85103238611#tab=citedBy

U2 - 10.1080/07357907.2021.1903914

DO - 10.1080/07357907.2021.1903914

M3 - Article

C2 - 33720792

AN - SCOPUS:85103238611

SN - 0735-7907

VL - 39

SP - 315

EP - 320

JO - Cancer Investigation

JF - Cancer Investigation

IS - 4

ER -

Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis

Abstract

Keywords

ASJC Scopus subject areas

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