Organocatalytic enantioselective conjugate additions to enones

Jian Wang, Hao Li, Liansuo Zu, Wei Jiang, Hexin Xie, Wenhu Duan, Wei Wang

Research output: Contribution to journalArticlepeer-review

255 Scopus citations

Abstract

Conjugate addition reactions of a wide range of nucleophilic enol species with enones, catalyzed by a cinchona alkaloid derived thiourea organocatalyst, have been developed with attending good yields and high enantioselectivities under a mild reaction condition. The general method provides an efficient approach to the preparation of versatile building blocks possessing various functional groups.

Original languageEnglish (US)
Pages (from-to)12652-12653
Number of pages2
JournalJournal of the American Chemical Society
Volume128
Issue number39
DOIs
StatePublished - Oct 4 2006
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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