Abstract
An organocatalytic, enantioselective conjugate addition reaction of nitroalkanes with nitroolefins has been developed under neat conditions without using an organic solvent. The process, catalyzed by a modified Cinchona alkaloid, affords synthetically useful 1,3-dinitro compounds in good yields (70-82%) with good degrees of enantioselectivity (67-88% ee).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2047-2050 |
| Number of pages | 4 |
| Journal | Advanced Synthesis and Catalysis |
| Volume | 348 |
| Issue number | 15 |
| DOIs | |
| State | Published - Oct 2006 |
| Externally published | Yes |
Keywords
- Asymmetric catalysis
- C-C bond formation
- Michael addition
- Organic catalysis
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry
Fingerprint
Dive into the research topics of 'Organocatalytic, enantioselective conjugate addition of nitroalkanes to nitroolefins'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS