Organocatalytic, enantioselective conjugate addition of nitroalkanes to nitroolefins

Jian Wang, Hao Li, Liansuo Zu, Wei Jiang, Wei Wang

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


An organocatalytic, enantioselective conjugate addition reaction of nitroalkanes with nitroolefins has been developed under neat conditions without using an organic solvent. The process, catalyzed by a modified Cinchona alkaloid, affords synthetically useful 1,3-dinitro compounds in good yields (70-82%) with good degrees of enantioselectivity (67-88% ee).

Original languageEnglish (US)
Pages (from-to)2047-2050
Number of pages4
JournalAdvanced Synthesis and Catalysis
Issue number15
StatePublished - Oct 2006
Externally publishedYes


  • Asymmetric catalysis
  • C-C bond formation
  • Michael addition
  • Organic catalysis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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