Abstract
An unprecedented organocatalytic asymmetric Michael addition of fluorine-containing carbon-centered nucleophiles to nitroolefins has been described. The process features the creation of a fluorine-containing quaternary carbon center and an adjacent chiral carbon center adducts with good to excellent level of enantioselectivity.
| Original language | English (US) |
|---|---|
| Article number | C00309SS |
| Pages (from-to) | 1525-1530 |
| Number of pages | 6 |
| Journal | Synthesis |
| Issue number | 9 |
| DOIs | |
| State | Published - May 2009 |
| Externally published | Yes |
Keywords
- Cinchona alkaloid
- Conjugate addition
- Fluorination
- Nitroolefin
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry
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