Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

Jian Wang; Hao Li; Wenhu Duan; Liansuo Zu; Wei Wang

doi:10.1021/ol0519137

Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

Jian Wang, Hao Li, Wenhu Duan, Liansuo Zu, Wei Wang

Research output: Contribution to journal › Article › peer-review

261 Scopus citations

Abstract

(Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.

Original language	English (US)
Pages (from-to)	4713-4716
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	21
DOIs	https://doi.org/10.1021/ol0519137
State	Published - Oct 13 2005
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol0519137

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@article{1471c7cceec340d1b348c3d321215460,

title = "Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins",

abstract = "(Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.",

author = "Jian Wang and Hao Li and Wenhu Duan and Liansuo Zu and Wei Wang",

year = "2005",

month = oct,

day = "13",

doi = "10.1021/ol0519137",

language = "English (US)",

volume = "7",

pages = "4713--4716",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "21",

}

TY - JOUR

T1 - Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

AU - Wang, Jian

AU - Li, Hao

AU - Duan, Wenhu

AU - Zu, Liansuo

AU - Wang, Wei

PY - 2005/10/13

Y1 - 2005/10/13

N2 - (Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.

AB - (Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.

UR - http://www.scopus.com/inward/record.url?scp=27144522622&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27144522622&partnerID=8YFLogxK

U2 - 10.1021/ol0519137

DO - 10.1021/ol0519137

M3 - Article

C2 - 16209517

AN - SCOPUS:27144522622

SN - 1523-7060

VL - 7

SP - 4713

EP - 4716

JO - Organic Letters

JF - Organic Letters

IS - 21

ER -

Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

Abstract

ASJC Scopus subject areas

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