Organocatalytic asymmetric michael addition of 2,4-pentandione to nitroolefins

Jian Wang, Hao Li, Wenhu Duan, Liansuo Zu, Wei Wang

Research output: Contribution to journalArticlepeer-review

252 Scopus citations


(Chemical Equation Presented) A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities.

Original languageEnglish (US)
Pages (from-to)4713-4716
Number of pages4
JournalOrganic Letters
Issue number21
StatePublished - Oct 13 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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