Organocatalysis: Asymmetric cascade reactions catalysed by chiral secondary amines

Xinhong Yu, Wei Wang

Research output: Contribution to journalArticlepeer-review

492 Scopus citations


The utilisation of chiral secondary amines as promoters for asymmetric cascade reactions has been subject of intensive research in asymmetric organocatalysis in the past few years. Key developments in this area are highlighted in this review. As shown, these powerful synthetic methodologies serve as efficient approaches to the construction of complex chiral molecular architectures from simple achiral materials in one-pot transformations under mild conditions with high stereocontrol.

Original languageEnglish (US)
Pages (from-to)2037-2046
Number of pages10
JournalOrganic and Biomolecular Chemistry
Issue number12
StatePublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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