Abstract
Multispectral imaging was investigated as a technique to exploit the spatial and spectral information available in the diagnosis of atherosclerosis. A diagnostic system is proposed that could provide direct viewing of a standard endoscopic or a total-fluorescence image. In addition, multiple spectral-feature images, each associated with a separate, narrow spectral band, could be obtained and processed to produce an optimized contrast image. In this study, a 'white-light' image and a total-fluorescence image were obtained. In addition, a three-dimensional, multispectral data set was generated, and two methods of utilizing this data were explored: 1) a per-pixel ratio of fluorescence intensities, and 2) an optimized superposition of the spectral-feature images. Fluorescence imaging is found to provide a rich data set possessing great potential for improving the detection and characterization of atheromatous disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 16-27 |
| Number of pages | 12 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 1425 |
| State | Published - 1991 |
| Event | Proceedings of Diagnostic and Therapeutic Cardiovascular Interventions - Los Angeles, CA, USA Duration: Jan 20 1991 → Jan 22 1991 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering