Abstract
Genetically encoded optical actuators and indicators have changed the landscape of neuroscience, enabling targetable control and readout of specific components of intact neural circuits in behaving animals. Here, we review the development of optical neural interfaces, focusing on hardware designed for optical control of neural activity, integrated optical control and electrical readout, and optical readout of population and single-cell neural activity in freely moving mammals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 103-129 |
| Number of pages | 27 |
| Journal | Annual Review of Biomedical Engineering |
| Volume | 16 |
| DOIs | |
| State | Published - Jul 2014 |
| Externally published | Yes |
Keywords
- channelrhodopsin
- GCaMP
- halorhodopsin
- imaging
- neurophysiology
- optogenetics
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Biomedical Engineering
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