Abstract
This chapter describes the combination of optical coherence tomography (most commonly used to visualize the microstructure of tissue) with light-induced fluorescence (which probes the biochemical composition of tissue). This combination has synergistic potential to accurately identify disease, or to elucidate the basic structure and function of tissue. Because the two imaging modalities have very different capabilities and technical requirements, combination into a dual-modality instrument can be challenging, yet can be accomplished in many different configurations. This chapter will examine the motivation for combined systems, several different instrumentation implementations, and example successful applications.
| Original language | English (US) |
|---|---|
| Title of host publication | Advanced Biophotonics |
| Subtitle of host publication | Tissue Optical Sectioning |
| Publisher | CRC Press |
| Pages | 279-298 |
| Number of pages | 20 |
| ISBN (Electronic) | 9781439895825 |
| ISBN (Print) | 9781439895818 |
| State | Published - Apr 19 2016 |
Keywords
- Colon
- Detectors
- Eye
- Fluorescence
- Imaging instrumentation
- Light sources
- Optical coherence tomography
- Optical fibers
- Skin
ASJC Scopus subject areas
- Engineering(all)
- Physics and Astronomy(all)
- Biochemistry, Genetics and Molecular Biology(all)