One-step: In vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

Duo Mao; Fang Hu; Guobin Qi; Shenglu Ji; Wenbo Wu; Deling Kong; Bin Liu

doi:10.1039/c9mh01675a

One-step: In vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

Duo Mao
, Fang Hu
, Kenry
, Guobin Qi
, Shenglu Ji
, Wenbo Wu
, Deling Kong
, Bin Liu

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

A bacterial metabolic probe combining d-alanine and a photosensitizer with aggregation-induced emission (AIE) has been developed for in vivo light-up imaging of bacterial walls and efficient antibacterial therapy. This activatable probe could serve as a promising non-antibiotic tool for diagnosis and treatment of biofilms and intracellular bacteria, as well as multi-resistant bacterial infections.

Original language	English (US)
Pages (from-to)	1138-1143
Number of pages	6
Journal	Materials Horizons
Volume	7
Issue number	4
DOIs	https://doi.org/10.1039/c9mh01675a
State	Published - Apr 2020
Externally published	Yes

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Process Chemistry and Technology
Electrical and Electronic Engineering

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10.1039/c9mh01675a

Cite this

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title = "One-step: In vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections",

abstract = "A bacterial metabolic probe combining d-alanine and a photosensitizer with aggregation-induced emission (AIE) has been developed for in vivo light-up imaging of bacterial walls and efficient antibacterial therapy. This activatable probe could serve as a promising non-antibiotic tool for diagnosis and treatment of biofilms and intracellular bacteria, as well as multi-resistant bacterial infections.",

author = "Duo Mao and Fang Hu and Kenry and Guobin Qi and Shenglu Ji and Wenbo Wu and Deling Kong and Bin Liu",

note = "Publisher Copyright: {\textcopyright} 2020 The Royal Society of Chemistry.",

year = "2020",

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T2 - In vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

AU - Mao, Duo

AU - Hu, Fang

AU - Kenry,

AU - Qi, Guobin

AU - Ji, Shenglu

AU - Wu, Wenbo

AU - Kong, Deling

AU - Liu, Bin

PY - 2020/4

Y1 - 2020/4

N2 - A bacterial metabolic probe combining d-alanine and a photosensitizer with aggregation-induced emission (AIE) has been developed for in vivo light-up imaging of bacterial walls and efficient antibacterial therapy. This activatable probe could serve as a promising non-antibiotic tool for diagnosis and treatment of biofilms and intracellular bacteria, as well as multi-resistant bacterial infections.

AB - A bacterial metabolic probe combining d-alanine and a photosensitizer with aggregation-induced emission (AIE) has been developed for in vivo light-up imaging of bacterial walls and efficient antibacterial therapy. This activatable probe could serve as a promising non-antibiotic tool for diagnosis and treatment of biofilms and intracellular bacteria, as well as multi-resistant bacterial infections.

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UR - https://www.scopus.com/pages/publications/85083200847#tab=citedBy

U2 - 10.1039/c9mh01675a

DO - 10.1039/c9mh01675a

M3 - Article

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JO - Materials Horizons

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One-step: In vivo metabolic labeling as a theranostic approach for overcoming drug-resistant bacterial infections

Abstract

ASJC Scopus subject areas

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