One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction

Hao Li; Jian Wang; Timiyin E-Nunu; Liansuo Zu; Wei Jiang; Shaohua Wei; Wei Wang

doi:10.1039/b611502k

One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction

Hao Li, Jian Wang, Timiyin E-Nunu, Liansuo Zu, Wei Jiang, Shaohua Wei, Wei Wang

Research output: Contribution to journal › Article › peer-review

158 Scopus citations

Abstract

A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of α,β-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.

Original language	English (US)
Pages (from-to)	507-509
Number of pages	3
Journal	Chemical Communications
Issue number	5
DOIs	https://doi.org/10.1039/b611502k
State	Published - 2007
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b611502k

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title = "One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction",

abstract = "A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of α,β-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.",

author = "Hao Li and Jian Wang and Timiyin E-Nunu and Liansuo Zu and Wei Jiang and Shaohua Wei and Wei Wang",

year = "2007",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction

AU - Li, Hao

AU - Wang, Jian

AU - E-Nunu, Timiyin

AU - Zu, Liansuo

AU - Jiang, Wei

AU - Wei, Shaohua

AU - Wang, Wei

PY - 2007

Y1 - 2007

N2 - A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of α,β-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.

AB - A highly enantioselective (S)-diphenylpyrrolinol triethylsilyl ether promoted tandem oxa-Michael-aldol reaction of α,β-unsaturated aldehydes with salicylaldehydes has been developed; the method affords one-pot access to chiral and synthetically useful chromenes in high yields and high enantioselectivities from readily available compounds.

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DO - 10.1039/b611502k

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JO - Chemical Communications

JF - Chemical Communications

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ER -

One-pot approach to chiral chromenes via enantioselective organocatalytic domino oxa-Michael-aldol reaction

Abstract

ASJC Scopus subject areas

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