On the rate of genetic adaptation under natural selection

L. R. Ginzburg; R. F. Costantino

doi:10.1016/0022-5193(79)90358-8

On the rate of genetic adaptation under natural selection

L. R. Ginzburg, R. F. Costantino

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

For a one locus n-allele genetic model of natural selection two theoretical predictions are obtained: first, that the non-equilibrium average fitness value, W(t) is always between the equilibrium value, W*, and W*-H(p_o, p*) t until finally W(t) = W* and, secondly, that the area bounded by W* and the curve W(t) is equal to H(p₀,p*), the entropy distance between initial (p₀) and equilibrium (p*) gene frequency distributions. The experimental observations corresponding to these predictions are discussed.

Original language	English (US)
Pages (from-to)	307-316
Number of pages	10
Journal	Journal of Theoretical Biology
Volume	77
Issue number	3
DOIs	https://doi.org/10.1016/0022-5193(79)90358-8
State	Published - Apr 7 1979
Externally published	Yes

ASJC Scopus subject areas

Statistics and Probability
Modeling and Simulation
General Biochemistry, Genetics and Molecular Biology
General Immunology and Microbiology
General Agricultural and Biological Sciences
Applied Mathematics

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AB - For a one locus n-allele genetic model of natural selection two theoretical predictions are obtained: first, that the non-equilibrium average fitness value, W(t) is always between the equilibrium value, W*, and W*-H(po, p*) t until finally W(t) = W* and, secondly, that the area bounded by W* and the curve W(t) is equal to H(p0,p*), the entropy distance between initial (p0) and equilibrium (p*) gene frequency distributions. The experimental observations corresponding to these predictions are discussed.

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On the rate of genetic adaptation under natural selection

Abstract

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