On the rate of genetic adaptation under natural selection

L. R. Ginzburg, R. F. Costantino

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


For a one locus n-allele genetic model of natural selection two theoretical predictions are obtained: first, that the non-equilibrium average fitness value, W(t) is always between the equilibrium value, W*, and W*-H(po, p*) t until finally W(t) = W* and, secondly, that the area bounded by W* and the curve W(t) is equal to H(p0,p*), the entropy distance between initial (p0) and equilibrium (p*) gene frequency distributions. The experimental observations corresponding to these predictions are discussed.

Original languageEnglish (US)
Pages (from-to)307-316
Number of pages10
JournalJournal of Theoretical Biology
Issue number3
StatePublished - Apr 7 1979
Externally publishedYes

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Agricultural and Biological Sciences(all)
  • Applied Mathematics


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