Of flaky tails and itchy skin

Donata Vercelli

doi:10.1038/ng0509-512

Of flaky tails and itchy skin

Donata Vercelli

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

A new study defines the flaky tail mouse as a model for human atopic dermatitis caused by a null mutation in the gene encoding filaggrin, a key component of the epidermal barrier. Research in these mice will help explain how a disrupted barrier contributes to the pathogenesis of atopic dermatitis and to asthma arising in the context of atopic skin disease.

Original language	English (US)
Pages (from-to)	512-513
Number of pages	2
Journal	Nature Genetics
Volume	41
Issue number	5
DOIs	https://doi.org/10.1038/ng0509-512
State	Published - May 2009

ASJC Scopus subject areas

Genetics

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10.1038/ng0509-512

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title = "Of flaky tails and itchy skin",

abstract = "A new study defines the flaky tail mouse as a model for human atopic dermatitis caused by a null mutation in the gene encoding filaggrin, a key component of the epidermal barrier. Research in these mice will help explain how a disrupted barrier contributes to the pathogenesis of atopic dermatitis and to asthma arising in the context of atopic skin disease.",

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AB - A new study defines the flaky tail mouse as a model for human atopic dermatitis caused by a null mutation in the gene encoding filaggrin, a key component of the epidermal barrier. Research in these mice will help explain how a disrupted barrier contributes to the pathogenesis of atopic dermatitis and to asthma arising in the context of atopic skin disease.

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JO - Nature Genetics

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Of flaky tails and itchy skin

Abstract

ASJC Scopus subject areas

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